The art of water transport in aquaporins. aquaporins are membrane water channels that play critical roles in controlling the water contents of cells. these channels are widely distributed in all kingdoms of life, including bacteria, plants, and mammals. more than ten different aquaporins have been found in human body, and several diseases, such as. The expression of aquaporins is regulated at both transcriptional and post-transcriptional levels via micrornas. however, in response to as, the proteins can be modified through phosphorylation and be degraded via the ubiquitin 26s proteasome system. further, a proposed model comprising reactive oxygen species, ca, ca-dependent kinases, and. Aquaporins are multifunctional membrane channels that facilitate the transmembrane transport of water and solutes. when transmembrane mineral nutrient transporters exhibit the same expression patterns as aquaporins under diverse temporal and physiological conditions, there is a greater probability that they interact..
Aquaporins (aqps) are a family of transmembrane channel proteins mainly responsible for the transport of water, but also may transport small uncharged molecules such as glycerol (borgnia & agre, 2001), urea (litman, sogaard, & zeuthen, 2009), ammonia (saparov, liu, agre, & pohl, 2007), hydrogen peroxide (bienert et al., 2007), arsenite (liu et al., 2002), and certain gases across biological membranes (bernardino et al., 2016).. Water transport through single-file pores poses a biophysical limitation on the efficiency with which aquaporins can transport water, so that aquaporins must be present in the membrane at a high density to increase membrane water permeability substantially 13). aquaporin-expressing cells generally contain several thousands, or more, aquaporins per μm² of membrane, as compared with ten or fewer ion channels per μm² of membrane..
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